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Anthony Viscogliosi, Small Bone Innovations, Inc. (212) 583-9700 ext. 2100
Nick Kilsby, Creative Partners PR, (203) 705-9202

SMALL BONE INNOVATIONS MAKES $250,000 RESEARCH GRANT TO THE AMERICAN FOUNDATION FOR SURGERY OF THE HAND

Three-year grant for research into treatment of arthritis in upper limbs


Seattle, WA: September 27, 2007 - Small Bone Innovations, Inc. (SBi), a single-source provider of products, technology and education for the small bone and joint sector of the orthopedic industry, announced today that it made a $250,000 grant to the American Foundation for Surgery of the Hand (AFSH). The unrestricted, three-year grant will be used to fund research into treatment of arthritis, such as arthroplasty, in the upper limbs from the fingertips to the elbow.

“We are at a point now where patients are not accepting procedures that resect anatomy or fuse joints. They are demanding the restoration of form and function in addition to relieving pain and, for many arthritis sufferers, this marks a shift away from medication to mitigation,” said Anthony G. Viscogliosi, Chairman and CEO of SBi.

“In my view, this shift is in great part due to advances in both technology and specialized skills, as in hand surgery, creating less invasive, tissue sparing and function restoring implants and resurfacing procedures that grants such as this are designed to support,” he added.

Anne J. Miller, MD President of the AFSH, noted that SBi is the first company to make a substantial contribution to the foundation’s recently launched Research Development Fund. “I also believe we are first non-profit organization in the field of orthopedics to actively reach out and embrace ethical cooperation between surgeons and the device industry.”

The award was officially announced during 62nd Annual Meeting of the American Society for Surgery of the Hand (ASSH) being held at the Washington State Convention & Trade Center in Seattle, WA (Sept. 26-30).
William H. Seitz, MD, of The Cleveland Clinic, an orthopedic surgeon noted for his pioneering work in treating defective upper limbs, said: “In exploring the potential for science and technology to change lives, it is not only essential to obtain private, yet unrestricted funding, but also to work with people like the Viscogliosi brothers who can ultimately help us convert concepts into best practices based on their proven, long term commitment to the advance of orthopedics.”

For more information on SBi, please visit: www.totalsmallbone.com. For more information on the AFSH and the ASSH conference, please visit: www.assh.org.

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About Small Bone Innovations, Inc.


Small Bone Innovations, Inc. (SBi) was founded in 2004 by Viscogliosi Bros., LLC, (VB), the New York-based merchant banking firm that specializes in the musculoskeletal/orthopedic sector. VB created SBi as the first company to focus purely on small bone & joint science. By integrating established companies and professionals in the field, SBi can offer a broad, clinically proven portfolio of products and technologies to treat trauma and diseases in small bones & joints. Today, SBi has more than 140 employees at facilities in New York, NY, Morrisville, PA and Minneapolis, MN.

SBi closed on the sale of $42.2 million of its securities in December 2005. At the time, based on data provided by Venture Source, this was the largest venture capital investment ever recorded in the field of orthopedic devices.
SBi was a 2006 recipient of Red Herring magazine's annual “"Red Herring 100 North America" award, recognized as one of the nation's leading technology companies and the only orthopedic device company selected among an initial entry of more than one thousand firms.

Additionally, SBi's Artelon CMC-I Spacer, developed for patients with thumb base osteoarthritis, was featured on the cover and highlighted within Medical Design Technology magazine's “"Year of Innovation" issue as one of the most fascinating technologies influencing the medical device industry.
Medical Device & Diagnostic Industry Magazine named SBi to their list of “"50 Companies to Watch" in 2006, noting, "Small Bone Innovations is going against the grain in its determination to become a market leader in the small bone & joint device sector."

For more information on SBi, please visit: www.totalsmallbone.com

About Viscogliosi Bros., LLC:

Established by Marc R. Viscogliosi, John J. Viscogliosi and Anthony G. Viscogliosi in New York City in 1999, Viscogliosi Bros., LLC (VB) was the first venture capital/private equity and merchant banking firm dedicated to the musculoskeletal/orthopedics sector of the health care industry.

Today, VB is a leading independent firm with a mission to create, build and finance companies founded on innovations developed by surgeons and uniquely focused on "life changing" musculoskeletal/orthopedic technologies. VB has worldwide surgeon, industry and trade relationships and significant financial expertise in the musculoskeletal/orthopedic sector.
As principals of VB, the Viscogliosi brothers have a combined total of nearly half a century of experience analyzing and investing in the musculoskeletal/orthopedics sector, directing literally billions of dollars through the orthopedics industry. They have pioneered innovative financial, strategic and management initiatives for nearly 150 companies in the sector, from start-up, seed and development stage all the way to exit, while helping thousands of people lead better lives through the orthopedic and spinal products marketed and sold by the companies they have assisted in developing and financing.

For more information on VB, go to: www.vbllc.com

Forward-looking statements

This press release may contain forward-looking statements as defined in the U.S. Private Securities Litigation Reform Act of 1995. Readers are cautioned not to place undue reliance on these forward-looking statements. Actual results may differ materially from those indicated by these forward-looking statements as a result of risks and uncertainties impacting the Company's business including increased competition; the ability of the Company to expand its operations and to attract and retain qualified professionals; technological obsolescence; general economic conditions; and other risks.

Copyright © Small Bone Innovations, Inc., 2005-2006.


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